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Two articles about the breakthrough in the design and synthesis of eukaryotic genomes published on Science by TJU research group.

2017-03-10
      In seven new studies, two of them are from Tianjin University, scientists of the Synthetic Yeast Genome Project (Sc2.0) who previously constructed a single yeast chromosome now report constructing five more chromosomes — representing more than one-third of yeast's entire genome.
      The results , published in the 10 March issue of Science, are major progress on the road to building the first fully synthetic eukaryotic — or nucleus-containing — organism, which the Sc2.0 consortium hopes to complete in the next two years by swapping all 16 yeast chromosomes for engineered ones. Such a genome, equipped with a full set of chromosomes that could be engineered to give new properties to yeast, would be ripe for customization.

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